2 New Genes Linked to ALS and Related Disorders

Recognition that the mutations adversely impact regulation of RNA could lead to targeted therapy to correct the problem. The mutation’s location in the prion-like domain might also prove significant. Although the mutations in hnRNPA2B1 or hnRNPA1 appear to be rare, hundreds of other RNA-binding proteins have prion-like domains. Taylor said patients with unexplained neurodegenerative diseases may have mutations in these proteins.

The Music Lives On: Dangerous Dan Toler

Long-time fans of the Allman Brothers were saddened to learn Feb. 27 that former guitarist Dan Toler died at the age of 65. Dan and his brother David “Frankie” Toler, a drummer, were involved with a number of bands over the years, including the Allman Brothers from 1979 to 1982. Contact Music shared the details [...]