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The RASCALS Foundation Announces Higher Education Scholarships for 2014

The RASCALS Foundation is pleased to announce that it is once again offering  the 2014 Higher Education Scholarship Program to assist families affected by ALS. We would like to acknowledge and thank our newest partner Helping Hands for ALS, a student group associated with John Burroughs High School for their generous participation in making these [...]

Acceleration of Clinical Program in ALS Confirms Proof of Efficacy Data Obtained in Animals

AB Science SA, a pharmaceutical company specialized in research, development and marketing of protein kinase inhibitors (PKIs), announces, following the press release from November 4, that the acceleration of the clinical development program in ALS is in line with proof of efficacy experiments conducted in two different models that generated positive results of increased survival.

Last Day to Pre-Register for the RASCALS Foundation 5K Walk/Run in Tower Grove Park, November 2nd

Please join the Robert A. Stehlin Campaign for ALS (RASCALS) to “Fight ALS One Step At A Time”
on Saturday, Nov. 2nd, Tower Grove Park.

Lou Gehrig’s Disease Twice as Likely to Strike Military Veterans

“We’re trying to prime the pump and fund (researchers) before they go into clinical trials,” said Melissa Forsythe, director of the Pentagon’s ALS Research Program. “Our goal every year is to make the very best investment we can.”

New ALS Drug Headed for Phase IIa Trial

Researchers at Houston Methodist Neurological Institute and elsewhere will soon begin phase IIa clinical trials of TDI-132, a drug that in animal models has shown promise in reducing the inflammation associated with Amyotrophic Lateral Sclerosis, also known as ALS or Lou Gehrig’s Disease.

Michael R. Brand Announced as New Secretary of RASCALS Board of Directors

The Robert A. Stehlin Campaign for ALS (R.A.S.C.A.L.S.) is pleased to announce the election of Michael R. Brand to the foundation’s Board of Directors as Secretary, his duties include ensuring that board business is conducted in compliance with its bylaws, providing fiscal oversight, and maintaining a continuity of policies and practices in keeping with 501(c)(3) legal requirements.

Cytokinetics Inc. Announces Initiation of First-Time-in-Humans, Phase I Clinical Trial of CK-2127107

Cytokinetics, Incorporated announced today the initiation of a first-time-in-humans, Phase I clinical trial of CK-2127107 in healthy male volunteers. Cytokinetics is developing CK-2127107, a novel small molecule activator of the fast skeletal muscle troponin complex, for the potential improvement of skeletal muscle function in diseases and medical conditions associated with neuromuscular dysfunction, muscular weakness, and/or muscle fatigue. Like tirasemtiv, the lead drug candidate from the company’s skeletal muscle activator program, CK-2127107 slows the rate of calcium release from the regulatory troponin complex of fast skeletal muscle fibers, which sensitizes the sarcomere to calcium.

Unique ALS ‘Exome-Sequencing’ Project Is Focus of New Grant

MDA has awarded a $400,000 grant to National Institutes of Health (NIH) Laboratory of Neurogenetics researchers to perform exome sequencing on samples taken from 1,000 people with sporadic amyotrophic lateral sclerosis (ALS). The project will be led by neurologist Bryan Traynor, head of the Neuromuscular Diseases Research Group at the NIH in Bethesda, Md.

NYSE Euronext Highlights World ALS Day in Netherlands

This morning, Eric Nolet, general director of the ALS Foundation of the Netherlands, opened the trading day by sounding the bell to highlight World ALS Day — or Wereld ALS Dag.

Saneron and South Texas Blood & Tissue Center to Collaborate

Saneron will use the cells for future clinical trials to study possible therapies for restoring brain tissue in patients suffering from Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), also known as “Lou Gehrig’s disease,” and the effects of stroke.