Posted by Site Administrator on February 12, 2013
“This new finding sheds light on how the mutation causes these disorders, and it provides us with a marker that helps us track disease progression in patients with this disorder and potentially combat the disease,” says senior author Leonard Petrucelli, Ph.D., a molecular neuroscientist and director of the Department of Neuroscience at Mayo Clinic in Florida.
Categories: Research News, Technology, Treatments
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Tags: ALS community, ALS medical care, ALS research, ALS research funding, ALS treatments, amyotrophic lateral sclerosis, biomarker ALS, Bob Stehlin, C9ORF72 gene, C9RANT, Department of Neuroscience at Mayo Clinic Florida, DNA sequence ALS, frontotemporal dementia, Leonard Petrucelli, Lou Gehrig's disease, Mayo Clinic, motor neuron cells, Motor Neuron Disease, National Institutes of Health, neurodegenerative disorders, neuronal death and toxicity, PALS, RASCALS Foundation, Robert A. Stehlin Campaign for ALS, St.Louis RASCALS ALS Lou Gehrig's Disease amotrophic lateral sclerosis
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Posted by Site Administrator on April 27, 2012
It is the first clinically available testing service for detecting hexanucleotide repeat expansion in the C9ORF72 gene. The test is offered to aid in the diagnosis of familial and sporadic ALS.
Categories: Research News, Technology
| Tags: ALS, ALS community, ALS genetic research, ALS research, American Academy of Neurology, American Academy of Neurology (AAN) Annual Meeting in New Orleans, amyotrophic lateral sclerosis, Athena Diagnostics, C9ORF72, C9ORF72 gene, Duke University ALS Clinic, frontotemporal dementia, Jeff Weisberg, Lou Gehrig's disease, Quest Diagnostics, RASCALS Foundation, Richard Bedlack, Robert A. Stehlin Campaign for ALS, St.Louis RASCALS ALS Lou Gehrig's Disease amotrophic lateral sclerosis, Steve Gleason, Team Gleason
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Posted by Site Administrator on March 27, 2012
by Michelle Pflumm, Ph.D., originally published online at ALS.net, February 28, 2012
FTLD Explained. FTLD occurs when certain regions of the brain including those involved in critical thinking, problem solving and complex decision-making shrink (red) due to neuronal loss. FTLD is also known as frontotemporal dementia (FTD). Here, an MRI of a person with a form [...]
Categories: Research News
| Tags: 9ORF72-linked ALS, ALS, amyotrophic lateral sclerosis, C9ORF72 gene, frontotemporal dementia, frontotemporal lobar degeneration, FTLD, Lou Gehrig's disease, Massachusetts General Hospital, Michelle Pflumm Ph.D., Orla Hardiman MD FRCP, RASCALS Foundation, Robert A. Stehlin Campaign for ALS, Robert Brown MD PhD, St.Louis RASCALS ALS Lou Gehrig's Disease amotrophic lateral sclerosis, Trinity College Dublin
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Posted by Site Administrator on January 13, 2012
“Although clinically they have always been described as two separate diseases, they are overlapping. We now believe that ALS and FTD are actually different clinical manifestations of the same disease.”
Categories: Research News
| Tags: ALS, ALS Association, ALS community, ALS research, amyotrophic lateral sclerosis, C9ORF72, chromosome 9, Dr. Bryan Traynor, frontotemporal dementia, frontotemporal dementia FTD, FTD, Lou Gehrig's disease, Lucie Bruijn, Mayo Clinic, Neuromuscular Diseases Research Group, RASCALS Foundation, Robert A. Stehlin Campaign for ALS, U.S. National Institutes of Health
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