What Causes Lou Gehrig’s Sticky Masses?

Globs of protein clustered in the neurons that control muscles have long been the hallmark of amyotrophic lateral sclerosis (ALS), the fatal neurodegenerative disease also commonly known as Lou Gehrig’s disease. Now, a study of the most commonly found mutant gene in people with ALS reveals an unexpected origin of some of those sticky masses, a finding that may offer drug developers a new target for treatments.

Categories: Research News, Treatments  |  Tags: ALS, ALS community, ALS research, ALS research funding, ALS treatments, ALS-FTD, amyotrophic lateral sclerosis, Barrow Neurological Institute in Phoenix, Bob Stehlin, Bryan Traynor, C9ORF72 gene, C9orf72 mutations, Dieter Edbauer, dipeptide repeat (DPR) proteins, GGGGCC-laden C9orf72, Lou Gehrig's disease, Ludwig Maximilians University Munich in Germany, National Institute on Aging in Bethesda Maryland, neurodegenerative process ALS, PALS, protein clusters ALS, RASCALS Foundation, Robert A. Stehlin Campaign for ALS, St.Louis RASCALS ALS Lou Gehrig's Disease amotrophic lateral sclerosis, TDP-43, University of Antwerp in Belgium  |  No comments