ALS TDI Enters Collaboration with to-BBB to Investigate Potential Treatments for ALS

CAMBRIDGE, Massachusetts, January 10, 2013 — The ALS Therapy Development Institute (ALS TDI) has entered into a new collaboration with to-BBB, a clinical stage biotechnology company focusing on enhanced drug delivery across the blood-brain barrier, to investigate potential treatments for ALS (aka Motor Neuron or Lou Gehrig’s disease).
“This partnership brings a new potential tool to [...]

ALS TDI and Gladstone Collaborate to Discover Potential ALS Treatments

The ALS Therapy Development Institute (ALS TDI) and the Gladstone Institutes today announced the formation of a research collaboration to speed the discovery of potential treatments for ALS through the preclinical drug development process.

ALS TDI Partners with Neurotune to Investigate Potential ALS Treatments

The ALS Therapy Development Institute (ALS TDI) announced today that it has entered into collaboration with Neurotune to investigate a potential treatment for ALS (aka Motor Neuron or Lou Gehrig’s disease).

Opinon: Off-Label Options and Compassionate Access to Phase II Drugs

With regard to the development of an efficacious treatment for ALS, we are still in its infancy. There is much more to be done—and much more quickly than we’ve seen.

Dilemma: When 1 Drug Treats 2 Diseases

Many patients with Lou Gehrig’s disease, a fatal disorder formally known as amyotrophic lateral sclerosis, may want to try the drug on their own—even though there’s no evidence that it is safe or effective in patients with the disease.

ALS Therapy Development Institute to Launch Phase II Clinical Trial of TDI 132 for ALS Patients

The ALS Therapy Development Institute (ALS TDI) will launch a Phase II clinical trial on TDI 132 (aka:fingolimod/Gilenya®) as a potential treatment for ALS (Lou Gehrig’s disease).